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    TriclosanChemicalProperties,Uses,ProductionDisinfectantsTriclosanisanefficientbroad-spectrumtopicalantimicrobsoresistanttoacidandalkalihydrolysiswit,(,hepatitisBvirus,etc.):itisfirstadsorbedonthebacterialcellwallandthenfurtherpenetratesthroughthecellwallandhasreactionwiththelipidandproteininthecytoplasm,a(healthsoap,healthlotion),removingunderarmodor(footaerosol),handsanitizer,wounddisinfectantsprays,medicalequipmentdisinfectants,hygienecleanser(cream),andaatmentofgingivitis,%.CarcinogenicityIn2004,ateacher()fromtheVirginiaTechUniversity(US)hadfoundfromtheexperimentsthatthereactionbetweenthetriclosan-containingproductandthechlorine-containingtapwatercontainingcangenerateasubstanceknownas"chloroformaryl",thatis,chloroform(chemicalname:trichloromethane)whichisacolorless,,,,boththeInternationalCancerResearchCentreandtheUnitedStateshavealreisthenewnationalstandardoftoothpaste(GB8372-2008)implementedonFebruary1,,thene,theprohibitedorrestrictedingredientsincludenearly1,500kinds,yaddittotherawmaterials,%.Triclosanwerelisted%.Thenewnationalstandardhasruledthatthefluorinecon%-%,%to011%℃(60-61℃).Itisslightlysolubleinwaterandsolubleinethanol,acetone,,emulsionsandresins;/,thedisinfectantsofmedicalinstrumentaswellasdietinstrumentaswellasthepreparationoftheanti-bacterial,IIfattyacidsynthase(FAS-II)ofbacteriaandparasites,andalsoinhibitsthemammalianfattyacidsynthase(FASN),,4-dichloro-phenolastherawmaterial;use2,4-dichloro-phenoltoreactwithpotassiumhydroxidetogeneratedichlorophenolpotassiumwhichfurtherreactswith2,5-dichloro-nitrobenzeneinthecatalysisofcopperforgenerationof2,4,4-trichloro-2-,4,4-trichloro-2-aminodiphenylether,and:havepotassi,togetherwithchlorineforchlorinationtoobtain2,4,4’-trichloro-2-,4,4-trichloro-2-,:AnaromaticetherthatisphenolwhichissubstitutedatC-5byachlorogroupandatC-2bya2,eproductssuchassoaps,skincreams,toothpasteanddeodoantsaswellasinhouseholditemssuchasplasticchoppingboards,,antiperspirants,,triclosanisincorporatedintotoothpaste();Stri-DexFaceWash().MechanismofactionTriclosanisacte,whichinadditiontoitsbroadantibacterialpropertycou,thecompoundisrapidlyreleasedfromoraltissues,resultinginrelativelypooranimalinhibitoryconcentrationvaluesgosaninapolyvinylmethylethermaleicacidcopolymer(PVM/MA,Gantrez).WiththecombinationofPVM/MAcopolymerandtriclosan,the%%PVM/roducts,includingsoaps,deodorants,mouthwashes,toothpastes,cosmetics,,tongue,esameproductandwhealsinvolvingherfaceafterkissi%–%.Aseverelocalizedurticarialreactionoccurredwithopentestingto2%;however,theauthorssuspectedthistobethecasebecauseofapositiveurticarialresponsetotriclosanwithin15minutes,ahistoryofangioedematothetriclosan-containingtoothpaste,andbecausenoimmediatereactionswereseeninfivecontrolsubjectswhowereopentestedto2%,oftenwithotheractiveingredients,triclosan’/,includingbothgram-positiveandgram-negativebacteriaandactsviainhibitingbacterMethyleneChlorideUsageAndSynthesisAlsoknownasmethylenedichlorideanddichloromethane,CH2Cl2isacolorless,volatileliquidwithapenetratingether-likeodorthatissolubleinalcoholandether,,solventdegreasing,,solventextraction,solventforcelluloseacetate,,/,andithasanoctanol/watercoefficient(logKow)(ppm).ersandremovers;asaprocesssolventinthemanufactureofdrugs,pharmaceuticals,andfilmcoatings;asametalcleaningandfinishingsolventinelectronicsmanufacturing;chaspaints,automotiveproducts,,hops,,duetoconcernoverresidualsolvent,(short-term)effectsofmethylenechlorideinhalationinhumansconsistmainlyofnervoussystemeffectsincludingdecreasedvisual,auditory,andmotorfunctions,(long-term)exposuretomethylenechloridesuggestthatthecentralnervoussystem(CNS),andindeedisalreadyincommercialuse,(掳C),methylenechlorideisasuspe,theconcendsthatworkersnotbeexposedtomorethan50ppmofthechemical,whiletheOccupationalSafetyandHealthAdministration鈥檚uireadditionalventilationequipment,,thechemicalisarecognizedenvironmentalpollutant,andboththefederalandstategovernment,inthenearfuture,plantsusingmethylenechlorideasanauxiliaryblowingagentmaybefacedwiththesubstantialadditionalexpenseofinstallingscrubbersorsimilarequipmenttoremovemethylenechloridefromairand/,Californiahasrecentlyproposedthatemissionsofmethylenechlorideinthatstatebesubjecttoaheavy鈥減ollution鈥tax,,,fats,waxes,resins,bitumen,,inpropellantmixturesforaerosolcontainers,asasolventforplastics,asadegreasingagent,asanextractingagentinthepharmaceuticalindustry,,petroleumnaphtha,removersincludingindustrialpaintandcommercialfurniturestrippers,homepaintremovers,,blister,mersion(dip),amethylenec,1,1-trichloroethaneinnonflammableadhesiveformulationsforindustrialapplications,,instantbonding,useofmethylenechlorideeliminatesthepossibilityofhardseamsandallowsforrea,aflammabilitysuppressant,vaporpressuredepressant,tionofslabstonofawidevarietyofmaterialsincludingoils,fats,,oleoresinextractionfromavarietyofspices,,ybemuchhigher,rsamplestake,markedareashouldbeestablishedwhereMethyleneChlorideishandled,usedorstoredasrequiredbytheOSHAMethyleneChlorideStandard().MethyleneChloridereactsviolentlyWithOXIDIZINGAGENTS(suchasPERCHLORATES,PEROXIDESPERMANGANATESCHLORATESNITRATESCHLORINE,BROMINEandFLUORINECHEMICALLYACTIVEMETALS(suchasPOTASSIUM,SODIUMMAGNESIUMandALUMINUM)andSTRONGBASES(suchasSODIUMHYDROXIDEandPOTASSIUMHYDROXIDE).MethyleneChlorideisnotcompatiblewithliquidoxygen;,roducts-->ChemicalProductsCASCatalogC90140,65092-53-7,C90123,14665-31-7,C53031900,1020251-53-9,C00984,3646-73-9,C11634,6874-98-2,C646,328968-36-1,C11237,1806-98-0,C10715,72520-92-4,C10465,491-74-7,C-247,845877-55-6,c,1310355-45-3,C1311,138154-39-9,C-492,24268-89-1,C18:1,19307-16-5,C-684,20064-00-0,501C-67,30123-86-5,C-45,28907-45-1,C-857,81483-73-0,C21:2,122768-03-0,C525,C829,65094-73-7,C18665,298C80,146494-40-8,64C87,C225,31930-67-3,192C86,139147-26-5,C684,20063-73-4,C29,70894-76-7,183C91,680C91,163239-22-3,C921-78,C205,6237-29-2,C39,59578-07-3,C-10,C4:0,102282-28-0,C264,6237-22-5,540C91,640C46,32155-21-8,C8-10,447C88,C137,13365-37-2,C76,24863-90-9,C325,6546-56-1,C75,191282-48-1,C31,5,8-14:2[1-14C],C2-8,C4:0,103404-95-1,31C,398515-96-3,C3:0,108321-21-7,CA125>>96,CA242,CA72-4>>96,CA24,39390-54-0,CA423,CA-074,134448-10-5,CA72-4,CA19-9,C3A(70-77),63555-63-5,C5a,CA19-965-85,CA15-3>>96,CAA,4c,7,7a,8,10,10a,11,13a-octahydrobenzo[f]cyclopenta[c]cyclopenta[4,5]pyrido[3,2,1-ij]quinoline-8-carboxylicacid,CAACAACGGCCCCTCGATA,,5855-78-7,CA2+-ACTIVATEDPHOSPHOLIPID-DEPENDENTSERINE-THREONINEKINASEDISOZYMEHUMAN,CA2+-ACTIVATEDPHOSPHOLIPID-DEPENDENTSERINE-THREONINEKINASEXISOZYMEHUMAN,CA2+-ACTIVATEDPHOSPHOLIPID-DEPENDENTSERINE-THREONINEKINASEGISOZYMEHUMAN,CA2+-ACTIVATEDPHOSPHOLIPID-DEPENDENTSERINE-THREONINEKINASE,EISOZYMEHUMAN,CA2+-ACTIVATEDPHOSPHOLIPID-DEPENDENTSERINE-THREONINEKINASEBIIISOZYMEHUMAN,CA2+-ACTIVATEDPHOSPHOLIPID-DEPENDENTSERINE-THREONINEKINASEHUMAN,CA2+-ACTIVATEDPHOSPHOLIPID-DEPENDENTSERINE-THREONINEKINASEHISOZYMEHUMAN,CAAGCTTG,5-PHOSPHORYLATED,CAAGCTTG,5-NON-PHOSPHORYLATED,CAAF2protein,CAAF1protein,Cab,Cabadox,Cabbage(leaf)/Brassicaoleracea-Inorganiccomposition(pleaseaskfordetailedinformation),Cabbage-Traceelements,Cabbage/Brassicaoleracea-Inorganiccomposition(pleaseaskfordetailedinformation),CABBAGEEXTRACT,CABBAGE(FREEZEDRIEDPOWDER),CABBAGEJUICE,CABBAGE(ETHANOLEXTRACT),CABBAGEROSE,:1,BrassicaAleracea,CabbageStemAndLeafPe50:1,BrassicaAleracea,CabbagePowder-Greenish-CreamColor,BrassicaAleracea,:1,BrassicaAleracea,CabbagePowder-CreamColor,BrassicaAleracea,CabbageFlakes/Powder,Cabbage,ext.,89958-13-4,CABBAGE-TRACEELEMENTS(CRMSTANDARD),CA-ALALLOY,CABBAGEALLERGEN,CABBAGESEEDEXTRACT,CABBAGEPOWDER,CABBAGES,乐透手机版登陆ExemestaneChemicalProperties,Uses,ProductionIndicat,androstenedione,(producedbytheadrenalcortex)teit,thusdramatical,itcanrartificiallivepostmenopausaladvancedbreastcancer,anditcanalsobeusedtotreatmoinhibitaromatase,itstillhasnonoti%.Post,,,anditsoverallbindingratetoproteinis90%.Itismainlymetabolizedbytheliver,themetaboliteisinactive17-Hydrecoxetron,,whichbothaccountfor42%,butwhenusedincombinationwithastrongCYP3A4inhibitor(Ketoconazole),etics,butitisalsopossiblet,dryness,constipation,diarrhea,dizziness,insomnia,rash,fatigue,fever,swelling,pain,vomiting,abdominalpain,increasedappetite,weightgain,,someliteraturereportscasesofhypertension,depression,anxiety,difficultybreathing,coughing,,abnormalitiesinliverfunctionindicators(suchasalanineaminotransferase),,25mgofExemestane,qd,canachieveanobjectiveefficacyrateof15-28%,,Exemestanecanstillachieveanobjectiveefficacyrateof11-13%.%onpatientswhohavenotrespondedtonon-steroidalaromataseinhibitors,,breastfeedingwomen,rateforthebiosynthesisofestrogen,androstanedione,andcanbesynthesizedbymethylidenationofandrosta-1,4-d,soinducinginvivoadose-relateyactivearomataseinhibitorswithahighlypotentandselectivemechanismofaction,,10to100mglkgofexemestanadministeredpotwice-dailyfor4weeksresultedin76to88%,thisagent,italiaCarloErba(Italy)UsesAnantineoplastic(hormonal)UsesantiinfectiveUsesLabeledExemestane,intendedforuseasaninternalsta:A17-oxosteroidthatisandrosta-1,4-diene-3,17-dioneinwhicht(oestrogensynthase)system,(Pharmacia&Upjohn).GeneralDescriptionExemestane,6-methylenandrosta-1,4-diene-3,17-dione(Aromasin),isthefirststeroid-basedaromatase%to95%within2to3days,tiallynointeractionwithsteroidreceptors,β-hydroxyexemestanereductionproduct,however,hasmuchhigheraffinityfortheARthantheparent(stillseveralfoldlessthanDHT,%%formetabolite).TheclinicalsignificanceoftheaffiAstaxanthinChemicalProperties,Uses,ProductionProductfeaturesShrimpflavinisfoundinrivercrayfishshell,oystersandsalmon,whichisasortofredcarotenoid,Itcanbecombinedwiththeproteininvivoandshowgreen,,anti-aging,anti-tumor,,,andhasuniquecoloringfunction,alsocanpromoteantibodyproduction,,theabilityisstrongerthanβ-carotene((10times).Itissolubleinwaterandlipophilic,solubleincarbondisulfide,acetone,,andhasabroadprospectinfood,feed,cosmetics,,Pluvialismicroalgae,Phaffiarhodozyma,wildsalmon,shrimp,salmon,,butnoteveryonecangetenough,,isakindofprecioushealthingredients,isusedfordevelopmenttoenhanceimmunity,anti-oxidation,anti-inflammatory,eyesandbrainhealth,,themainusedasarawmaterialforhumanhealthfoodandmedicine;aquaculture(currentlythemainsalmon,troutandsalmon),simmunity,becauseofitsnon-specificcombinationwithskeletalmuscle,caneffectivelyremovethefreeradicalswhicharegeneratedbythemovementofthemusclecells,strengthenaerobicmetabolism,,withtrueanti-ag,Itcaneffectivelywrinkleanti-aging,mprovementofretinalfunction,(-OH)atendsofthemolecule,astaxanthincanbeesterification,%ofnaturalastaxanthinisexistinesterform,,therefore,thestabilityisnotthesame,/4,soitisonlynaturalantioxidantof1/,astaxanthin,protein,calciumpowderandbiologicalfertilizerfromshrimpshell,itsproductionprocessisasfollows::1-2,,thetemperatureoftheenzymesolutionwas30-70℃,pHvaluewas4-8,thetimewas2-6hours,%-1%,thetemperatureisupto70-100℃,addingorganicsolventextraction,theweightratiooforganicsolventandshrimpshellwas1:1-2,,,isakindofprecioushealthingredients,isusedfordevelopmenttoenhanceimmunity,anti-oxidation,anti-inflammatory,eyesandbrainhealth,,themainusedasarawmaterialforhumanhealthfoodandmedicine;aquaculture(currentlythemainsalmon,troutandsalmon),simmunity,becauseofitsnon-specificcombinationwithskeletalmuscle,caneffectivelyremovethefreeradicalswhicharegeneratedbythemovementofthemusclecells,strengthenaerobicmetabolism,(1)peroxidationandreducesoxidativedamageofLDL-cholesterol(therebyreducingarterialplaqueformation),cells,cellmembranes,(2)AstaxanthinseemstoimprmersandParkinsonsdisease.(3)Astaxanthinprotectstheeyes(4)-,:MethodsofproductionAmmoniaisoxidatedtonitrousoxidegas,tedtomelt,addingasmallamountofmetalliclead,,,filtered,withdilutenitricacidandfiltratecorrectly,theevapor,itobtai:Thecontainingtailgasisremovedfromabsorptionaccesstothebottominthedilutenitricacidproductionprocess,theconsumptionofsodiumcarbonatesolutionof20%~30%downfromthetowerspraytoabsorbnoxintheexhaustgas,~,thecontentofsodiumcarbonateis3~5g/L,theagentofarsenicandheavymetalremovalagentpurification,filtrationtoremoveimpuritiessuchasarsenicandheavymetals,therefinedsolutionbyevaporating,coolingcrystallization,centrifugalseparation,drying,+NO+N02→2NaNO2+CO2Na2CO3+2N02→NaNO2+NaNO3+CO2Thecentrifugalseparationofthemotherliquor,/NO2rati,~,thecontentofsodaashis3~5g/Landsendtoevaporation,absorbliquidevaporationconcentrationat132℃,thencoolto75℃,precipitationsodiumnitriteincrystallization,thenthroughseparation,+NO+NO2→2NaNO2+CO2CategoryoxidizingagentToxicitygradinghightoxicAcutetoxicityOrallyadministered:ratsLD50:85mg/kg,miceLD50:175mg/kgStimulusdataEyes-Rabbit500mgmildExplosivehazardcharacteristicsMixedwithreducingagent,heat,impact,frictioncanbeexplosiveCombustiblehazardTheheatdecompositioncanproducetoxicnitrogenoxideandsodiumoxidesmokeStorageandtransportationcharacteristicsWarehouseventilationandlowtemperaturedrying;separatestoragewithorganicmatter,reducingagent,andotherflammablematerials,,sandysoilProfessionalstandardsTWA1mg/m3,STET3mg/m3ChemicalPropertiesSodiumnitrite,NaN02,isafire-hazardous,air-sensitive,yellowishwhitepowderthatissolubleinwateranddecomposesattemperaturesabove320C(608F).Sodiumnitriteisusedasanintermediatefordyestuffsandforpicklingofmeat,indyeingoftextiles,inrustproofing,inmedicine,μMUsesmanufactureofdiazodyes,nitrosoCompounds,andinmanyotherprocessesofmanufactureoforganicchemicals;dyeingandprintingtextilefabrics;bleachingflax,silk,andlinen;,coloringandpreserving;,:Ayellowhygroscopiccrystallinecompound,NaNO2,solubleinwater,slightlysolubleinetherandinethanol;rhombohedral;;°C;decomposesabove320°epreparationofnitrousacid(reactionwithcolddilutehydrochloricacid).So:finelydivided,,spontaneousdecompositioncan,&,tin(II)chlorideorotherreducingagentsmayreactexplosively[].Ifcontaminatedbyammoniumcompounds,spontaneousdecomposition,whichisveryreactiveandeasilyexplosive[Mellor2,:15661963].Meltingtogetherwilhanammoniumsaltleadstoaviolentexplosion[].inelydivided,,avigorousreactionoccursattendedbyflame[Mellor2:].HazardDangerousfireandexplosionriskwhenheatedto537C(1000F)orincontactwithreducingmaterials;;(orinhalationofexcessiveamountsofdust)causesrapiddropinbloodpressure,persistentandthrobbingheadache,vertigo,palpitations,andvisualdisturbances;skinbecomesflushedandsweaty,latercoldandcyanotic;othersymptomsincludenausea,vomiting,diarrhea(sometimes),fainting,,inhalation,subcutaneous,intravenous,:motoractivitychanges,coma,decreasedbloodpressurewithpossiblepulserateincreasewithoutfallinbloodpressure,arteriolarorvenousdlation,nauseaorvomiting,;,,NH4salts,cellulose,LI,(K+NH3),,butadene,phthalicacid,phthalicanhydride,reductants,sodlumamide,sodmmdisulfite,sodiumthocyanate,(/g)bycoolingto0o,(SeeKNO2.)SodiumnitritePreparationProductsAndRawmaterialsRawmaterialsUsesPalladiumisatransitionmetaleleme,silver,andcopperalloysindentistry;foralloybearings,springs,balancewheelsofwatches;formirrorsinastronomicalinstruments;ascatalyzerinmanufactureofsulfuricacidandinotheroxidizingprocesses;inpowderformascatalystinhydrogenationandinignitionofhydrogenorhydrocarbonswithoxygen;thespongy’sabilitytoabsorblargeamountsofhydrogenmakesitanexcellentcatalystforchemicalrandforhydrogenationofliquidvegetableoilsintosolidforms,roughthinsheetsofpalladium,wherethepurehydrogenpassesthroughthemetal’scrystalstructure,,electricalcontacts,springsforwatchesandclocks,high-qualitysparkplugs,andspecialwiresandas“whitegold”,i:Chemicalelement(nickelgroupelementatom):Pd;°C;°C;(20°C);;:(seealsoplatinummetals);;;;°C;±1°,,mostcompoundsbeingcomplexesofpalladium(II)withsomepalladium(IV).ItwasdiscoveredbyWilliamWoolaston(1766–1828)ction;canalsocopper,nickelsulfideorepreparationofcopper,nickelproductionprocessasaby-productasrawmaterials,,erials,addingaquaforextraction,filtration,addingammoniaandhydrochloricacidtoreact,,filtration,%,palladiumistheleastnoblemetal,,altho,mostofwhicharefour-coordinatedsquareplanarcomplexesofthemetalin+,palladiumformsablackoxide,,,,dium(II)nitrate,Pd(NO3),PdSO4,,(II)chloride,,themetalswells,,suchabsorptionactivatesmolecularhydrogen,’scompoundsareoxidizingagents,gadsorbedhydrogenarepyrophoric,,likemostmaterialsinpowderform,,palladium(symbolPd),butissl°,,but,likegold,°Cathinprotectiveoxideformsinair,butattemperaturesfrom790°Cthisfilmdecomposesbyoxygenloss,arnishdevelops;however,alloyi,whereitisusedasanalloywithsilverforelectricalcontact,palladiumoncarbonshouldalwaysbehandledunderaninertatmosphere(preferablyargon),andreafiltrationrequirescarefulhandlingbecauseitisusuall,andthemoistmaighlyactiveandreadilycauseignitionofhydrogen/airandsolvent/hissubstanceshouldbecoveredinwater,placedinanappropriatecontainer,clearlylabeled,andhandledaccordingtoyourinstitutionSynthesisofMelatoninPinealcellsobtaintryptophanfrombloodcirculationandbecome5-hydroxytryptophanecatalyzedbyhydroxylaseand5-hydroxytryptophan:forthefirstpartitmayturninto5-hydroxyl-benzpyroleaceticacidwhendeaminatedbymonoamineoxidase;foranotherpart,some5-hydroxytryptaminewillleavethepinealcellandbetakeninbysympatheticnerveendingandstoredwithneurotransmitterandnoradrenalin;fortheremainingpart,the5-hydroxytryptaminewillbeacetylatedbyN-acetyl-5-hydroxytryptaminetransferaseandthenbeo-methoxybyhydroxylationindole-o-methylconverzyme,,melatoninwillbereleasedbycellsandenterintobloodcirculationthroughcerebrospinalfluidordirectly,wherenoradrenalinmaystrengthenthesynthesis,,6-hydroxylmelatoninisformed,soonafterwardsitcombineswithglucuronicacidandsulfate,induction,modifiescircadianrhythm,antioxidant,freeradicalscavengerUsesImmunostimulant;MelatoninreceptorligandUsesMelatoninhascomplexeffectsonapoptoticpathways,inhibitingapoptosisini/:Amemberoftheclassofacetamidesthatisacetamideinwhichoneofthehydrogensattachedtothenitrogenatomisreplacedbya2-(5-methoxy-1H-indol-3-yl)(WHO)Melatoninispromotedasacurefortravelsickness,jet-lagandinsomniaandharmaciesasa"nutritionalsupplement",disp-XinNordicbreeds,caninepatternbaldness,,onestudy(Bubenik,)demonstratedthat5mg/tionProductsIodineChemicalProperties,Uses,ProductionElementofhalogenⅧoftheperiodictable,,:Atomicnumber53;;electronicconfiguration2,8,18,18,7;;℃(iodide),+Ⅴ(iodate),+Ⅶ(periodate).,dseaweed,theremainingmotherliquoraddedsulfuricacidproducedvioletsteamwithheating,,,%.Thereisasmallamountofiodideionintheseawater,,(IO3),olyzed,,andthecolorofsolutionispurple,,suchascarbontetrachloride,,suchaswater,,,solvationdoesntexist,,,,,;reactswithfluorine,chlorineandbrominerespectivelytoproducefluoride,chlorideandbromide;reactswithammoniantoproduceexplosivetriiodide;reactswithplatinumonlyathightemperatures;,itreactswithphospite,bisulfite,thiosulfate,arseniteandstannitetosulfate,tetrasulfate,,sulfurdioxideisoxidizedtosulfuricacid,,i,,suchashydrogensulphateandsodiumthiosulfate:(1)I2+H2S=S+2HI(2)I2+2S2O32-=S4O62-+2I-;Thelatterreactioncanbeusedtoquantifyiodineinanalyticalchemistry,,chlorinecouldoxidizeiodinetoiodicacid;inalkalinesolutions,,iodineiscombinedwithallthemetaltoproduceiodide;combinedwithnon-metaltoproducecovalentiodide;combinedwithotherhalogenstoproduceinterhalogencompounds,suchasiodideiodide,iodineiodide,,,butoxygenintheaircanoxidizeiodidetofreeiodine,,,inwhich(I3-I2),,,soil,water,,,andtheiodin,anditflowsintotheriverandlake,,~60g/,withabout400,(snow),/,,theconcentrationofiodimentsofthehumanbody,maintainingthebody~50mginadultbody,distributedinthemuscle,thyroid,skin,bones,(thyroxine)secretedbythyroid,accountingforabout20%ofthetotalamountofiodine(about8mg),sothephysiol,promotingproteinsynthesis,growthandmentaldevelopment,maintainingnormalmentalstate,metabolism,bodyshape,,sopregnantwomenshouldintakeiodineappropriately,eatingseafood,suchaskelp,,iodizedsaltispromotedinChina,withtheamountof1:20000to1:50000,;iodinetreatmentquicklyimprovesthesymptomsinthyroidcrisis;appropriateiodineisneededinpreoperativehyperthyroidismsurgery;iodinecanalsobeusedtotreatcertainoculardiseases,promotingexudateabsorptionandsoon;iodinecanalsobemadeofcontrastagentforurinarytractretrogradeangiographyandcholangiography;iodineiswidelyusedforskindisinfectionandsterilization;iodoformisusedformucosaldeepprocessinginthewound;,,ChineseNutritionSocietyrecommendedthatthedailysupplyofiodineis150gforadult,,iodinecontentofsandysoilsintheplateauareaisveryfew;,forexample,sulfocompound(isothiocyanate)fromcrucifersandperchloratefromothersourcesinhibitbeneficiationofiodideofthyroid;thioureaandthiouracilcontainthiol(-SH),interferingtheoxidationofiodideesses:Plantsintakeiodinefromthesoilandwater,sotheplantsiodinecontentisgenerallyhigherthantheexternalenvironment,whichistheone-levelconcentrationofiodine;Animalseatplants,sothattheanimalsiodinecontentishigherthantheplant,whichisthesecondaryconcentrationofiodine;Peopleeatanimalsandplants,:Theiodinecontentofseafoodisgreaterthanthatofterrestrialfood:Becauseseaisanaturaliodinelibrary,,suchaskelp,seaweed,freshfish,drycockles,clamdry,scallops,mussels,seacucumber,,anddryseaweedcanreach240mg/kgormore;followedbyseashellfishandfreshfish(800g/kgorso).However,theiodinecontentofsaltisextremelysmall,/,he/sheonlygetslessthan50giodine,:Inlandfood,eggandmilkhavehigheriodine(40~90g/kg),followedbymeat,,ollows:80%~90%isfromfood;10%~20%isfromdrinkingwater;lessthan5%,skin,respiratorytract,:(iodide)isabsorbedinthestomachandsmallintestinewithalmost100%.Organiciodineisdigestedanddeiodinizedinthedigestivetract,d,,fluorideandmagnesiuminthegastrointestinaltractblockabsorptionofiodine,,,,accountingformorethan80%oftotaliodineexcretion(ofwhichmorethan90%isinorganiciodine,and10%orlessisorganiciodine).Theiodineinthefecesismainlyorganiciodinethatisnotabsorbed,accountingforabout10%,buttheamountcouldreach30%lk,,theamountoflostiodinethroughthebreastwillbegreatlyincreased,,anditcouldkillbacteriaspores,fungi,(I2).Theprincipleisasfollows:iodinehasaneffectofiodizationandoxidizationonactivegroupofthebacterialprotein,andthenitcombineswithaminogroup,leadingtop,thesolubilityincreas,appropriateamountofpotassiumiodideisaddedtopromoionofiodine:moleculariodine(I2),triiodideions(I3-)andhypolodousacid(HIO).Amongthem,HIOlesshasthestrongestbactericidaleffect;andthenI2times;,,2%iodinetinctureisusedforskindisinfection,and5%,andintensityisproportionaltotheconcentration,soafteralittledryofiodinetincture,weshouldwipeitwith75%ethanol,preventingblistering,,%iodinesolutionwithoutethanolissuitableforsuperficialskindamageandwound,,%,,ough,snivel,tears,fever,headache,conjunctivitis,parotidglandenlargement,bronchitis,rhinitis,diplopia,stigmata,,,he/sheshouldleavethesceneimmediatelytobreathefreshairoutdoor,andtheninhale5%sodiumthiosulfateor2%,mouthandthroatwith2%,youshouldrinsewithwater,,,youshoulddrinkstarchpaste,milk,/,,longboots,latexgloves,

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